Science ??, doubt it Mate , either have a Custom Rod made up or consistently check out Rods at you local or favourite Fishing store for type of Rod your after that sits comfortably in your hand , feels balanced and right weight class for the Fish your after.
Spin or Cast , , then comes a reel that sits in the Realseat being not too heavy and not too light again matching the line class of the Rod i would say and that would be a balanced outfit .
An unbalanced outfit you soon get sick of using but a nice sometimes lighter feel than normal outfit is comfortable and gets the Fish tio the side without effort or stress or at least my view ey .
Look around and you can balance outfits at your local tackle store most times too.
Bet you allready thought the same way ey ??.