Gazza, i think its hard to draw a single rule around singles versus twins performance. For me the hull is the biggest factor, some hulls love the twins and shrug of the weight whilst a big single works for others. I went from a single 225 v6 yammy, 6 pots for a total of 4.2 litres to twin 140 zukes for a total of 4 litres. Yammy was spinning a 19 3 blade whilst zukes have got 18 3 blades. Boat 6.8 20 degree deadrise platey, heavy boat, big chine so dragging some hull in the water. Yammy was better for top speed but pretty much 1km per litre. Zukes are slower by 3 knots, better on hole shot and 1.1 to 1.2 km per litre. I recon the full width integrated pod (versus conventional pod) is must to handle the weight. Thats what i found on my boat anyway if it helps.
Scott